Journal of Biological Chemistry
Glycobiology and Extracellular MatricesGranule-stored MUC5B mucins are packed by the non-covalent formation of N-terminal head-to-head tetramersStructure of stored MUC5B mucin
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This work was supported by the Swedish Research Council; the Swedish Cancer Foundation; the Knut and Alice Wallenberg Foundation; the Inga Britt and Arne Lundberg Foundation; Sahlgrenska University Hospital (ALF); the Wilhelm and Martina Lundgren Foundation; NIAID, National Institutes of Health Grant U01AI095473; the Erica Lederhausen Foundation; the Magnus Bergvall Foundation; the Swedish Heart-Lung Foundation; the Center for Innovative Medicine (Karolinska Institutet); the Lederhausen Center for Cystic Fibrosis Research at the University of Gothenburg; the Swedish Cystic Fibrosis Foundation; and the Cystic Fibrosis Foundation (CFFT, Hansso14X0, and Thornt077X0). The authors declare that they have no conflicts of interest with the contents of this article. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
This article contains Figs. S1–S3 and Movies S1 and S2.
The 3D map has been deposited at Electron Microscopy Data Bank (EMDB) with id. EMD-4296.
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Both authors contributed equally to this work.