Journal of Biological Chemistry
Volume 293, Issue 4, 26 January 2018, Pages 1178-1191
Protein Synthesis and DegradationDeubiquitylase USP9X suppresses tumorigenesis by stabilizing large tumor suppressor kinase 2 (LATS2) in the Hippo pathway
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anaphase-promoting complex
LATS2
USP9X
ubiquitination
deubiquitination
protein stability
tumor suppressor gene
signal transduction
Hippo pathway
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This work was supported by National Key R&D Program of China Grant 2017YFA0504502, National Natural Science Foundation of China Key Project Grant 81730069, Excellent Young Scholars Project Grant 31422036, General Project Grant 31471316, International Collaboration Project Grant 31661130150, 111 Project Grant B13026, the Qianjiang Scholar Plan of Hangzhou, the Thousand Young Talents Plan of China, and the Academy of Medical Sciences (United Kingdom) Newton Advanced Fellowship (to B. Z.). The authors declare that they have no conflicts of interest with the contents of this article.
This article contains Figs. S1–S6.
© 2018 by The American Society for Biochemistry and Molecular Biology, Inc.