Journal of Biological Chemistry
Volume 290, Issue 1, 2 January 2015, Pages 56-64
Signal TransductionRole of Apoptosis Signal-regulating Kinase 1 (ASK1) as an Activator of the GAPDH-Siah1 Stress-Signaling Cascade*
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open access
Nuclear Translocation
Oxidative Stress
Protein Phosphorylation
Protein Translocation
Protein-Protein Interaction
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)
Seven in absentia homolog 1 (Siah1)
Apoptosis Signal-regulating Kinase 1 (ASK1)
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This work was supported by United States Public Health Service Grants MH-084018 (to A. S.), MH-094268 Silvo O. Conte Center (to A. S.), MH-069853 (to A. S.), MH-085226 (to A. S.), MH-088753 (to A. S.), MH-092443 (to A. S.), National Institutes of Health NRSA F31 Grant 1F31NS070459-01A1 (to C. T.), Stanley (to A. S.), RUSK (to A. S.), S-R foundations (to A. S.), NARSAD (to A. S. and N. S.), and Maryland Stem Cell Research Fund (A. S.). This work was also supported in part by Grant-in-aid 22580339 for Scientific Research from the Japan Society for the promotion of Science (to H. N).
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These authors contributed equally to this work.
© 2015 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.