Journal of Biological Chemistry
Volume 289, Issue 8, 21 February 2014, Pages 5158-5167
Molecular Bases of DiseaseThe Hypertrophic Cardiomyopathy Myosin Mutation R453C Alters ATP Binding and Hydrolysis of Human Cardiac β-Myosin*
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open access
Actin
Cardiac Muscle
Cardiomyopathy
Fluorescence
Kinetics
Myosin
Homology Models
Protein Structure-Function
Sequence Alignment
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- *
This work was supported, in whole or in part, by National Institutes of Health Grants T32 GM65013 (University of Colorado Molecular Biophysics Training Grant; to J. D.) and GM29090 (to L. A. L.). This work was also supported by Wellcome Trust Program Grant 085309 (to M. A. G.).
This article contains supplemental Figs. S1–S4.
- 1
Present address: Biomolecular Research Group, Department of Geographical and Life Sciences, Canterbury Christ Church University, Canterbury CT1 1QU, UK.
- 2
Present address: Dept. of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520.
© 2014 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.