Journal of Biological Chemistry
Volume 285, Issue 43, 22 October 2010, Pages 32869-32877
MetabolismAdipose Tissue-specific Inhibition of Hypoxia-inducible Factor 1α Induces Obesity and Glucose Intolerance by Impeding Energy Expenditure in Mice*,
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open access
Hypoxia
Insulin resistance
Metabolic diseases
Mitochondria
Obesity
Adipose Tissue Biology
Brown Adipose Tissue
Energy Expenditure and Obesity
Thermogenesis
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This work was supported by Research Grants Council of Hong Kong General Research Fund Grant HKU 7645/06M and Collaborative Research Fund Grant HKU 2/07C, Natural Science Foundation of China Grant 30600300, and an Outstanding Young Researcher Award from the University of Hong Kong (to A. X.).
The on-line version of this article (available at http://www.jbc.org) contains supplemental Figs. S1–S8.
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Supported in part by an HKU small project grant.
© 2010 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.