Journal of Biological Chemistry
Volume 285, Issue 12, 19 March 2010, Pages 8695-8702
Signal TransductionMD-2-mediated Ionic Interactions between Lipid A and TLR4 Are Essential for Receptor Activation*
Under a Creative Commons license
open access
Immunology/Innate Immunity
Immunology/LPS
Immunology/Toll Receptors
Membrane/Proteins
Methods/Computer Modeling
Methods/Fluorescence
Methods/Site-directed Mutagenesis
Protein/Structure
Cited by (0)
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This work was supported, in whole or in part, by National Institutes of Health Grants GM54060 (to D. T. G.) and AI057588 (to E. L.).
The on-line version of this article (available at http://www.jbc.org) contains supplemental Table S1 and Figs. S1–S8.
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Both authors contributed equally to this work.
© 2010 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.