Journal of Biological Chemistry
MECHANISMS OF SIGNAL TRANSDUCTIONDiacylglycerol (DAG)-lactones, a New Class of Protein Kinase C (PKC) Agonists, Induce Apoptosis in LNCaP Prostate Cancer Cells by Selective Activation of PKCα*
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Published, JBC Papers in Press, October 2, 2001, DOI 10.1074/jbc.M107639200
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This work was supported in part by United States Department of Defense Prostate Cancer Research Program Grant DAMD17-00-1-0531 and National Institutes of Health Grant R01 CA89202-01A1 (to M. G. K.).The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
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Recipient of a postdoctoral fellowship from Fundación Ramón Areces (Spain).
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To whom correspondence and reprint requests should be addressed: Center for Experimental Therapeutics, University of Pennsylvania School of Medicine, 816 Biomedical Research Bldg. II/III, 421 Curie Blvd., Philadelphia, PA 19104-6160. E-mail: [email protected].