Journal of Biological Chemistry
Volume 290, Issue 50, 11 December 2015, Pages 29781-29793
Molecular Bases of DiseaseDirect Melanoma Cell Contact Induces Stromal Cell Autocrine Prostaglandin E2-EP4 Receptor Signaling That Drives Tumor Growth, Angiogenesis, and Metastasis*
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open access
angiogenesis
bone
metastasis
prostaglandin
tumor microenvironment
B16 melanoma
Bone resorption
EP4 receptor
host-cancer interaction
prostaglandin E
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- *
This work was supported by Grants-in-Aid for Scientific Research 25460062 (to C. M.) and 23590069 (to M. I.), National Institute of Health Grant AR40994 (to H. N.), Arthritis Research UK (to H. N.), Cancer Research UK (to G. M.), and the Global Innovation Research Organization in Tokyo University of Agriculture and Technology (to M. I. and H. N.). The authors declare that they have no conflicts of interest with the contents of this article. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
© 2015 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.