Journal of Biological Chemistry
Volume 290, Issue 35, 28 August 2015, Pages 21553-21567
Signal TransductionAkt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-mediated Degradation*
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open access
E3 ubiquitin ligase
phosphorylation
ubiquitin ligase
ubiquitylation (ubiquitination)
Wnt signaling
Akt
Cul4
DDB1
Pygo2
Cited by (0)
R01-GM083089R21CA161807R01GM074830National Institutes of Health
- *
This work was supported, in whole or in part, by National Institutes of Health Grants R01-GM083089 (to X. D.) and R21CA161807 and R01GM074830 (to L. H.). This work was also supported by Susan G. Komen Grant KG110897 (to X. D.). The authors declare that they have no conflicts of interest with the contents of this article.
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Supported by California Breast Cancer Research Program Postdoctoral Fellowship 14FB-0129.
© 2015 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.