Journal of Biological Chemistry
Volume 285, Issue 29, 16 July 2010, Pages 22276-22281
Molecular BiophysicsMolecular Mechanism of Type I Collagen Homotrimer Resistance to Mammalian Collagenases*
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Collagen
Enzyme Kinetics
Extracellular Matrix
Metalloprotease
Protein Degradation
Collagen Homotrimer
Matrix Metalloproteinase
Tissue Remodeling
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- *
This work was supported, in whole or in part, by National Institutes of Health NICHD Intramural Research Program grant (to S. L.) and NIDDK Grant DK069522 (to C. L. P.). This work was also supported by National Science Foundation Grant PHY-0750371 (to W. L.) and Wellcome Trust Program Grant 075473 (to H. N.).
The on-line version of this article (available at http://www.jbc.org) contains supplemental Equations S1–S21, Fig. S1, and additional references.
© 2010 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.