Skip to main content
Log in

Regionalization of R&D activities: (Dis)economies of interdependence and inventive performance

  • Published:
Journal of International Business Studies Aims and scope Submit manuscript

Abstract

This paper examines the impact of the extent of the regionalization of MNEs’ R&D activities on their inventive performance. By joining the regionalization theory with the recombinant view of invention, we challenge the implicit assumption that all foreign knowledge-seeking activities will necessarily offer new knowledge to the firm. We introduce the (dis)economies of interdependence, defined as the (dis)advantages that the firm derives due to the interdependence among countries within a region, as a new theoretical mechanism explaining the benefits and costs of regionalization. Our analysis of global pharmaceutical firms shows that an inverted U-shaped relationship exists between the number of regions in which a firm has R&D activities and its inventive performance. Our results also indicate that a firm’s recombinant capability moderates the inverted U-shaped relationship in such a way that, when a firm’s recombinant capability is high, it reaches its turning point in a larger number of regions and the inverted U-shaped relationship is flatter. These results underscore that recombinant capability significantly influences the firm’s ability to derive benefits and reduce costs from the regionalization of its R&D activities. Our findings suggest that it is through the consideration of the (dis)economies of interdependence that offers the essential reasoning needed to unwind the inferred assumption that all foreign knowledge-seeking activities will offer access to new knowledge.

Résumé

Cet article examine l’impact de l’ampleur de la régionalisation des activités de R&D des EMN sur leur performance inventive. En associant la théorie de la régionalisation à la vision recombinante de l’invention, nous remettons en question l’hypothèse implicite selon laquelle toutes les activités de recherche de connaissances à l’étranger offriront nécessairement de nouvelles connaissances à l’entreprise. Nous présentons les (dés)économies d’interdépendance, définies comme les (dés)avantages que l’entreprise tire de l’interdépendance entre les pays d’une région, comme un nouveau mécanisme théorique expliquant les avantages et les coûts de la régionalisation. Notre analyse d’entreprises pharmaceutiques mondiales montre qu’il existe une relation en forme de U inversé entre le nombre de régions dans lesquelles une entreprise a des activités de R&D et sa performance inventive. Nos résultats indiquent également que la capacité de recombinaison d’une entreprise modère la relation en forme de U inversé de telle sorte que lorsque la capacité de recombinaison d’une entreprise est élevée, elle atteint son point d’inflexion dans un plus grand nombre de régions et la relation en forme de U inversé est plus plate. Ces résultats soulignent que la capacité de recombinaison influence de façon significative la capacité de l’entreprise à tirer des avantages et à réduire les coûts de la régionalisation des activités de R&D. Nos résultats suggèrent que c’est par la prise en compte des (dés)économies d’interdépendance que l’on obtient le raisonnement essentiel nécessaire pour démanteler l’hypothèse inférée selon laquelle toutes les activités de recherche de connaissances à l’étranger donneront accès à de nouvelles connaissances.

Resumen

Este artículo examina el impacto del alcance de la regionalización de las actividades de I + D de las EMN en su desempeño inventivo. Al unir la teoría de regionalización con la visión recombinante de la invención, retamos la suposición implícita que todas las actividades en búsqueda de conocimiento en el extranjero necesariamente van a ofrecer nuevo conocimiento a la empresa. Introducimos las (des) economías de interdependencia, definidas como las (des) ventajas de que la empresa obtiene debido a la interdependencia entre los países dentro de una región, como un nuevo mecanismo teórico para explicar los beneficios y costos de la regionalización. Nuestro análisis de empresas farmacéuticas globales muestra que una relación invertida en forma de U invertida existe entre el número de regiones en los cuales una empresa tiene actividades de I + D y su desempeño inventivo. Nuestros resultados también indican que la capacidad recombinante de una empresa modera la relación en forma de U invertida de tal manera que cuando la capacidad recombinante de una empresa es alta, esta alcanza su punto de inflexión en un mayor número de regiones y la relación en forma de U invertida es plana. Estos resultados recalcan que la capacidad recombinante influencia significativamente la habilidad de la empresa para obtener beneficios y reducir costos de la regionalización de las actividades de I + D. Nuestros hallazgos sugieren que es a través de la interdependencia de las (des) economías que ofrece el razonamiento esencial necesario para deshacer la suposición deducida de que todas las actividades de búsqueda de conocimiento en el extranjero van a ofrecer acceso a nuevo conocimiento.

Resumo

Este artigo examina o impacto da extensão da regionalização das atividades de P&D das MNEs em seu desempenho inventivo. Ao mesclar a teoria da regionalização à visão recombinante da invenção, desafiamos a suposição implícita de que todas as atividades de busca de conhecimento estrangeiras necessariamente oferecerão novos conhecimentos à empresa. Introduzimos as (des) economias de interdependência, definidas como as (des) vantagens que a empresa obtém devido à interdependência entre os países de uma região, como um novo mecanismo teórico que explica os benefícios e custos da regionalização. Nossa análise de empresas farmacêuticas globais mostra que existe uma relação em forma de U invertido entre o número de regiões nas quais uma empresa possui atividades de P&D e seu desempenho inventivo. Nossos resultados também indicam que a capacidade recombinante de uma empresa modera o relacionamento em forma de U invertido de tal maneira que quando a capacidade recombinante de uma empresa é alta, ela atinge seu ponto de virada em um número maior de regiões e o relacionamento em forma de U invertido é mais plano. Esses resultados ressaltam que a capacidade recombinante influencia significativamente a capacidade da empresa de obter benefícios e reduzir custos com a regionalização de atividades de P&D. Nossas descobertas sugerem que é através da consideração das (des) economias de interdependência que oferecem o necessário racional essencial para relaxar a inferida suposição de que todas as atividades estrangeiras de busca de conhecimento oferecerão acesso a novos conhecimentos.

Chinese

本文研究跨国公司研发活动的区域化程度对其发明绩效的影响。通过将区域化理论与发明重组观相结合, 我们对所有外国寻求知识活动必将为公司提供新知识的隐含假设提出挑战。我们介绍了相互依赖的(反)经济, 它定义为公司由于区域内国家之间的相互依赖而获得的(反)优势, 作为解释区域化收益和成本的新理论机制。我们对全球制药公司的分析表明, 公司从事研发活动区域的数量与其发明创造之间存在倒U型关系。我们的结果还表明, 企业的重组能力以一种方式调节倒U形关系, 即当企业的重组能力较高时, 它会在更多数量的区域达到转折点, 且倒U形关系更加平坦。这些结果强调, 重组能力极大地影响了该公司从研发活动的区域化中获得收益并降低成本的能力。我们的发现表明, 正是通过考虑提供必要的推理来推断推论假设的相互依赖的(反)经济, 所有外国寻求知识的活动将提供获取新知识的途径。

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1
Figure 2
Figure 3

Similar content being viewed by others

REFERENCES

  • Abud, M. J., Hall, B., & Helmers, C. 2015. An empirical analysis of primary and secondary pharmaceutical patents in Chile. PLoS ONE, 10(4): e0124257. https://doi.org/10.1371/journal.pone.0124257.

    Article  Google Scholar 

  • Ahuja, G., & Katila, R. 2001. Technological acquisitions and the innovation performance of acquiring firms: A longitudinal study. Strategic Management Journal, 22(3): 197–220.

    Google Scholar 

  • Ahuja, G., & Katila, R. 2004. Where do resources come from? The role of idiosyncratic situations. Strategic Management Journal, 25(8–9): 887–907.

    Google Scholar 

  • Ahuja, G., & Lampert, C. M. 2001. Entrepreneurship in the large corporation: A longitudinal study of how established firms create breakthrough inventions. Strategic Management Journal 22(6–7): 521–543.

    Google Scholar 

  • Ahuja, G., Lampert, C. M., & Tandon, V. 2008. Moving beyond Schumpeter: Management research on the determinants of technological innovation. Academy of Management Annals, 2(1): 1–98.

    Google Scholar 

  • Almeida, P. 1996. Knowledge sourcing by foreign multinationals: Patent citation analysis in the U.S. semiconductor industry. Strategic Management Journal, 17(S2): 155-165.

  • Almeida, P., & Kogut, B. 1999. Localization of knowledge and the mobility of engineers in regional networks. Management Science, 45(7): 905–917.

    Google Scholar 

  • Almeida, P., & Phene, A. 2004. Subsidiaries and knowledge creation: The influence of the MNC and host country on innovation. Strategic Management Journal, 25(8–9): 847–864.

    Google Scholar 

  • Almodóvar, P. & Rugman, A.M. 2014. The M Curve and the Performance of Spanish International New Ventures. British Journal of Management, 25(SI): S6–S23.

    Google Scholar 

  • Archibugi, D., & Michie, J. 1995. The globalisation of technology: A new taxonomy. Cambridge Journal of Economics, 19(1): 121–140.

    Google Scholar 

  • Arregle, J. L., Beamish, P. W., & Hébert, L. 2009. The regional dimension of MNE’s foreign subsidiary localization. Journal of International Business Studies, 40(1): 86–107.

    Google Scholar 

  • Arregle, J-L., Miller, T. L., Hitt, M. A., & Beamish, P. W. 2013. Do regions matter? An integrated institutional and semiglobalization perspective on the internationalization of MNEs. Strategic Management Journal, 34(8): 910–934.

    Google Scholar 

  • Banalieva, E. R., & Dhanaraj, C. 2013. Home-region orientation in international expansion strategies. Journal of International Business Studies, 44(2): 89–116.

    Google Scholar 

  • Banalieva, E. R., & Eddleston, K. A. 2011. Home-region focus and performance of family firms: The role of family vs non-family leaders. Journal of International Business Studies, 42(8): 1060–1072.

    Google Scholar 

  • Banbury, C. M., & Mitchell, W. 1995. The effect of introducing important incremental innovations on market share and business survival. Strategic Management Journal, 16(S1): 161–182.

    Google Scholar 

  • Bartlett, C. A., & Ghoshal, S. 1989. Managing across borders: The transnational solution. Boston, MA: Harvard Business School.

    Google Scholar 

  • Bausch, A., Fritz, T. & Boeseke, K. 2007. Performance effects of internationalization strategies: A meta-analysis. In A. M. Rugman (Ed.), Regional aspects of multinationality and performance: 143–176. Bingley, UK: Emerald Group Publishing Limited.

    Google Scholar 

  • Blau, P. 1977. Inequality and heterogeneity: A primitive theory of social structure. New York: The Free Press.

    Google Scholar 

  • Buckley, P. J., & Ghauri, P. N. 2004. Globalisation, economic geography and the strategy of multinational enterprises. Journal of International Business Studies, 35(2): 81–98.

    Google Scholar 

  • Bush, W. S., Oetjens, M. T., & Crawford, D. C. 2016. Unravelling the human genome–phenome relationship using phenome-wide association studies. Nature Reviews Genetics, 17(3): 129–145.

    Google Scholar 

  • Cantwell, J. 1989. Technological innovation and multinational corporations. Oxford, UK: Blackwell.

    Google Scholar 

  • Cantwell, J. 2009. Location and the multinational enterprise. Journal of International Business Studies, 40(1): 35–41.

    Google Scholar 

  • Carnabuci, G., & Operti, E. 2013. Where do firms’ recombinant capabilities come from? Intraorganizational networks, knowledge, and firms’ ability to innovate through technological recombination. Strategic Management Journal, 34(13): 1591–1613.

    Google Scholar 

  • CBO Report. 2006. Research and development in the pharmaceutical industry. Washington DC: Congressional Budget Office.

    Google Scholar 

  • Chen, Y., Lorenzi, N. M., Sandberg, W. S., Wolgast, K., & Malin, B. A. 2017. Identifying collaborative care teams through electronic medical record utilization patterns. Journal of the American Medical Informatics Association, 24(e1): e111–e120.

    Google Scholar 

  • Chung, W., & Alcacer, J. 2002. Knowledge seeking and location choice of foreign direct investment in the United States. Management Science, 48(12): 1534–1554.

    Google Scholar 

  • Contractor, F. J. 2012. Why do multinational firms exist? A theory note about the effect of multinational expansion on performance and recent methodological critiques. Global Strategy Journal, 2(4): 318–331.

    Google Scholar 

  • Danzon, P. M., Nicholson, S., & Pereira, N. S. 2005. Productivity in pharmaceutical-biotechnology R&D: The role of experience and alliances. Journal of Health Economics, 24(2): 317–339.

    Google Scholar 

  • Delios, A. & Beamish, P.W. 2005. Regional and global strategies of Japanese firms. MIR: Management International Review: 45(1): 19-36.

  • Denny, J. C., Ritchie, M. D., Basford, M. A., Pulley, J. M., Bastarache, L., Brown-Gentry, K., & Crawford, D. C. 2010. PheWAS: Demonstrating the feasibility of a phenome-wide scan to discover gene–disease associations. Bioinformatics, 26(9): 1205–1210.

    Google Scholar 

  • DiMasi, J. A., Hansen, R. W., & Grabowski, H. G. 2003. The price of innovation: New estimates of drug development costs. Journal of Health Economics, 22(2): 151–185.

    Google Scholar 

  • Doz, Y. L. & Wilson, K. 2012. Managing global innovation: Frameworks for integrating capabilities around the world. Boston, MA: Harvard Business Review

    Google Scholar 

  • Dunning, J. H. 1996. The geographical sources of competitiveness of firms: Some results of a new survey. Transnational Corporations, 5(3): 1–30.

    Google Scholar 

  • Dunning, J. H. 1998. Location and the multinational enterprise: A neglected factor? Journal of International Business Studies, 29(1): 45–66.

    Google Scholar 

  • Elango, B. 2004. Geographic scope of operations by multinational companies: An exploratory study of regional and global strategies. European Management Journal22(4): 431–441.

    Google Scholar 

  • FDA. 2002. FDA and the drug development process: How the agency ensures that drugs are safe and effective. FDA Fact Sheet, Publication Number FS 02-5, February. Food and Drug Administration: Rockville, MD.

  • Fleming, L. 2001. Recombinant uncertainty in technological search. Management Science, 47(1): 117–132.

    Google Scholar 

  • Flores, R. G., & Aguilera, R. V. 2007. Globalization and location choice: An analysis of US multinational firms in 1980 and 2000. Journal of International Business Studies, 38(7): 1187–1210.

    Google Scholar 

  • Florida, R. 1997. The globalization of R&D: Results of a survey of foreign-affiliated R&D laboratories in the USA. Research Policy, 26(1): 85–103.

    Google Scholar 

  • Froot, K. A. 1989. Consistent covariance matrix estimation with cross-sectional dependence and heteroskedasticity in financial data. Journal of Financial and Quantitative Analysis, 24(3): 333–355.

    Google Scholar 

  • Frost, T. S. 2001. The geographic sources of foreign subsidiaries’ innovations. Strategic Management Journal, 22(2): 101–123.

    Google Scholar 

  • Geroski, P., Machin, S., & Van Reenen, J. 1993. The profitability of innovating firms. The RAND Journal of Economics, 24(2): 198–211.

    Google Scholar 

  • Ghemawat, P. 2001. Distance still matters. Harvard Business Review, 79(8): 137–147.

    Google Scholar 

  • Ghemawat, P. 2003. Semiglobalization and international business strategy. Journal of International Business Studies, 34(2): 138–152.

    Google Scholar 

  • Ghemawat, P. 2005. Regional strategies for global leadership. Harvard Business Review, 83(12): 98–108.

    Google Scholar 

  • Ghemawat, P. 2007. Managing differences: The central challenge of global strategy. Harvard Business Review, 85(3): 58–68.

    Google Scholar 

  • Gilbert, D.U. & Heinecke, P. 2014. Success factors of regional strategies for multinational corporations: Exploring the appropriate degree of regional management autonomy and regional product/service adaptation. Management International Review, 54(5): 615–651.

    Google Scholar 

  • Gilman, D. 2010. The new geography of global innovation. New York: Global Markets Institute/Goldman Sachs.

    Google Scholar 

  • Giovannetti, G. T., & Morrison, S. W. 2000. Convergence: The biotechnology industry report. Palo Alto, CA: Ernst & Young.

    Google Scholar 

  • Girota, K., Terwiesch, C., & Ulrich, K. T. 2004. New drug development at Merck & Co. Philadelphia, PA: Wharton School Teaching Case.

    Google Scholar 

  • Girotra, K., Terwiesch, C., & Ulrich, K. T. 2007. Valuing R&D projects in a portfolio: Evidence from the pharmaceutical industry. Management Science, 53(9): 1452–1466.

    Google Scholar 

  • Haans, R. F. J., Pieters, C., & He, Z.-L. 2016. Thinking about U: Theorizing and testing U- and inverted U-shaped relationships in strategy research. Strategic Management Journal, 37(7): 1177–1195.

    Google Scholar 

  • Heinecke, P. 2011. Success factors of regional strategies for multinational corporations: Appropriate degrees of management autonomy and product adaptation. Berlin: Springer.

    Google Scholar 

  • Henderson, R. M., & Clark, K. B. 1990. Architectural innovation: The reconfiguration of existing product technologies and failure of established firms. Administrative Science Quarterly, 35(1): 9–31.

    Google Scholar 

  • Hilbe, J. M. 2011. Negative binomial regression, 2nd edn. Cambridge: Cambridge University Press.

    Google Scholar 

  • Hill, R. G. and Rang H. P. (Eds.) 2012. Drug discovery and development: Technology in transition, 2nd edn. London: Elsevier/Churchill Livingstone.

    Google Scholar 

  • Hitt, M.A., Bierman L, Uhlenbruck, K., & Shimizu, K. 2006. The importance of resources in the internationalization of professional service firms: The good the bad and the ugly. Academy of Management Journal, 49(6): 1137–1157.

    Google Scholar 

  • Hitt, M. A., Hoskisson, R. E., & Nixon, R. D. 1993. A mid-range theory of interfunctional integration, its antecedents and outcomes. Journal of Engineering and Technology Management, 10(1–2): 161–185.

    Google Scholar 

  • Jensen, J. B., Quinn, D. P., & Weymouth, S. 2015. The influence of firm global supply chains and foreign currency undervaluations on U.S. trade disputes. International Organization, 69(4): 913-947.

    Google Scholar 

  • Khanna, T., Kogan, J., & Palepu, K. 2006. Globalization and similarities in corporate governance: A cross-country analysis. Review of Economics and Statistics, 88(1): 69–90.

    Google Scholar 

  • Kim U. K., & Aguilera, R. V. 2015. The world is spiky: An internationalization framework for a semi-globalized world. Global Strategy Journal, 5(2): 113–132.

    Google Scholar 

  • Kim, D. J., & Kogut, B. 1996. Technological platforms and diversification. Organization Science, 7(3): 283–301.

    Google Scholar 

  • Kim, H. E., & Pennings, J. M. 2009. Innovation and strategic renewal in mature markets: A study of the tennis racket industry. Organization Science, 20(2): 368–383.

    Google Scholar 

  • Kogut, B., & Chang, S. 1991. Technological capabilities and Japanese foreign direct investment in the United States. Review of Economics and Statistics, 73(3): 401–414.

    Google Scholar 

  • Kogut, B., & Zander, U. 1992. Knowledge of the firm, combinative capabilities, and the replication of technology. Organization Science, 3(3): 383–397.

    Google Scholar 

  • Kogut, B. & Zander, U. 1993. Knowledge of the firm and the evolutionary theory of the multinational corporation. Journal of International Business Studies, 24(4): 625–645.

    Google Scholar 

  • Kuemmerle, W. 1997. Building effective R&D capabilities abroad. Harvard Business Review, 75(2): 61–70.

    Google Scholar 

  • Kuemmerle, W. 1999. The drivers of foreign direct investment into research and development: An empirical investigation. Journal of International Business Studies, 30(1): 1–24.

    Google Scholar 

  • Lahiri, N. 2010. Geographic distribution of R&D activity: How does it affect innovation quality? Academy of Management Journal, 53(5): 1194–1209.

    Google Scholar 

  • Lambert, D. 1992. Zero-inflated Poisson regression, with an application to defects in manufacturing. Technometrics, 34(1): 1–14.

    Google Scholar 

  • Lampert, C. M., & Kim, M. 2019. Going far to go further: Offshoring, exploration, and R&D performance. Journal of Business Research, 103: 376–386.

    Google Scholar 

  • Lampert, C. M., Kim, M., Hubbard, T. D., Roy, R., & Leckie, G. 2019. Fearlessly swimming upstream to risky waters: The role of geographic entry in innovation. Journal of Management Studies, 56(7): 1377–1413.

    Google Scholar 

  • Lee, J., & Kim, M. 2016. Market-driven technological innovation through acquisitions: The moderating effect of firm size. Journal of Management, 42(7): 1934–1963.

    Google Scholar 

  • Leiponen, A., & Helfat, C.E. 2010. Innovation objectives, knowledge sources, and the benefits of breadth. Strategic Management Journal, 31(2): 224–236.

    Google Scholar 

  • Leonard-Barton, D. 1995. Wellsprings of knowledge. Boston, MA: Harvard Business School

    Google Scholar 

  • Li, L., 2005. Is regional strategy more effective than global strategy in the US service industries? MIR: Management International Review, 45(1): 37-57.

    Google Scholar 

  • Lind, J. T., & Mehlum, H. 2010. With or without U? The appropriate test for a U-shaped relationship. Oxford Bulletin of Economics and Statistics, 72(1): 109–118.

    Google Scholar 

  • Liu, M., & La Croix, S. 2015. A cross-country index of intellectual property rights in pharmaceutical inventions. Research Policy, 44(1): 206–216.

    Google Scholar 

  • McNamara, G., & Vaaler, P. M. 2000. The influence of competitive positioning and rivalry on emerging market risk assessment. Journal of International Business Studies, 31(2): 337–347.

    Google Scholar 

  • Meyer, K. E., Mudambi, R., & Narula, R. 2011. Multinational enterprises and local contexts: The opportunities and challenges of multiple embeddedness. Journal of Management Studies, 48(2): 235–252.

    Google Scholar 

  • Mohr, A., Fastoso, F., Wang, C. & Shirodkar, V. 2014. Testing the regional performance of multinational enterprises in the retail sector: The moderating effects of timing, speed and experience. British Journal of Management, 25(SI): S100–S115.

    Google Scholar 

  • Mudambi, R., & Navarra, P. 2004. Is knowledge power? Knowledge flows, subsidiary power and rent-seeking within MNCs. Journal of International Business Studies, 35(5): 385–406.

    Google Scholar 

  • Mudambi, R., Pedersen, T., & Andersson, U. 2014. How subsidiaries gain power in multinational corporations. Journal of World Business, 49(1): 101–113.

    Google Scholar 

  • Narula, R. 2014. Exploring the paradox of competence-creating subsidiaries: balancing bandwidth and dispersion in MNEs. Long Range Planning, 47(1): 4–15.

    Google Scholar 

  • Nelson, R., R., & Winter, S. G. 1982. An evolutionary theory of economic change. Cambridge, MA: Harvard University Press.

    Google Scholar 

  • Nonaka, I., & Takeuchi, H. 1995. The knowledge-creating company: How Japanese companies create the dynamics of innovation. New York: Oxford University Press.

    Google Scholar 

  • Oh, C. H. & Contractor, F. 2014. A regional perspective on multinational expansion strategies: Reconsidering the three-stage paradigm. British Journal of Management, 25(S1): S42–S59.

    Google Scholar 

  • Oh, C. H., Kim, M., & Shin, J. 2019. Paths and geographic scope of international expansion across industries. International Business Review, 28(3): 560-574.

    Google Scholar 

  • Peissig, P. L., Costa, V. S., Caldwell, M. D., Rottscheit, C., Berg, R. L., Mendonca, E. A., & Page, D. 2014. Relational machine learning for electronic health record-driven phenotyping. Journal of Biomedical Informatics, 52: 260–270.

    Google Scholar 

  • Penner-Hahn, J., & Shaver, J. M. 2005. Does international research and development increase patent output? An analysis of Japanese pharmaceutical firms. Strategic Management Journal, 26(2): 121–140.

    Google Scholar 

  • Penrose, E. T. 1959. The theory of the growth of the firm. New York: Wiley.

    Google Scholar 

  • Petricevic, O., & Teece, D. J. 2019. The structural reshaping of globalization: Implications for strategic sectors, profiting from innovation, and the multinational enterprise. Journal of International Business Studies, 50(9): 1487–1512.

    Google Scholar 

  • PhRMA. 2009. Pharmaceutical industry profile. Washington, DC: Pharmaceutical Research and Manufacturers of America.

    Google Scholar 

  • PhRMA. 2015. Pharmaceutical industry profile. Washington, D.C.: Pharmaceutical Research and Manufacturers of America.

    Google Scholar 

  • Qian, G., Khoury, T. A., Peng, M. W., & Qian, Z. 2010. The performance implications of intra- and inter-regional geographic diversification. Strategic Management Journal, 31(9): 1018–1030.

    Google Scholar 

  • Qian, G., Li, L., Li, J., & Qian, Z. 2008. Regional diversification and firm performance. Journal of International Business Studies, 39(2): 197–214.

    Google Scholar 

  • Roberts, P. W. 1999. Product innovation, product–market competition and persistent profitability in the US. Strategic Management Journal, 20(7): 655–670.

    Google Scholar 

  • Roberts, E. B. 2007. Managing invention and innovation. Research Technology Management, 50(1): 35–54.

    Google Scholar 

  • Roberts, P. W., & Amit, R. 2003. The dynamics of innovative activity and competitive advantage: The case of Australian retail banking, 1981 to 1995. Organization Science, 14(2): 107–122.

    Google Scholar 

  • Rugman, A.M., & Oh, C., H. 2007. Multinationality and regional performance, 2001–2005. In A. M. Rugman (Ed.), Regional aspects of multinationality and performance (Research in Global Strategic Management, Volume 13): 31–43. Bingley, UK: EmeraldGroup Publishing Limited.

    Google Scholar 

  • Rugman, A. & Sukpanich, N. 2006. Firm-specific advantages intra-regional sales and performance of multinational enterprises. The International Trade Journal, 20(3): 355–382.

    Google Scholar 

  • Rugman, A. M., & Verbeke, A. 2004. A perspective on regional and global strategies of multinational enterprises. Journal of International Business Studies, 35(1): 3–18.

    Google Scholar 

  • Rugman, A. M., & Verbeke, A. 2005. Towards a theory of regional multinationals: A transaction cost economics approach. MIR: Management International Review, 45(SI): 5-17.

    Google Scholar 

  • Rugman, A. M., & Verbeke, A. 2007. Liabilities of regional foreignness and the use of firm-level versus country-level data: A response to Dunning et al. (2007). Journal of International Business Studies, 38(1): 200–205.

    Google Scholar 

  • Schotter, A., & Beamish, P. W. 2013. The hassle factor: An explanation for managerial location shunning. Journal of International Business Studies, 44(5): 521–544.

    Google Scholar 

  • Schumpeter, J. A. 1934. Theory of economic development. Cambridge, MA: Harvard University Press.

    Google Scholar 

  • Schumpeter, J. A. 1939. Business cycles. New York: McGraw-Hill

    Google Scholar 

  • Schumpeter, J. A. 1942. Capitalism, socialism, and democracy. New York: Harper & Brothers.

    Google Scholar 

  • Sharma, A., & Lacey, N. 2004. Linking product development outcomes to market valuation of the firm: The case of the US pharmaceutical industry. Journal of Product Innovation Management, 21(5): 297–308.

    Google Scholar 

  • Singh, J. 2008. Distributed R&D, cross-regional knowledge integration and quality of innovative output. Research Policy, 37(1): 77–96.

    Google Scholar 

  • Sood, A., & Tellis, G. J. 2009. Do innovations really pay off? Total stock market returns to innovation. Marketing Science, 28(3): 442–456.

    Google Scholar 

  • Sosa, M. L. 2009. Application-specific R&D capabilities and the advantage of incumbents: Evidence from the anticancer drug market. Management Science, 55(8):1409–1422.

    Google Scholar 

  • Stock, J. H., Wright, J. H., & Yogo, M. 2002. A survey of weak instruments and weak identification in generalized method of moments. Journal of Business & Economic Statistics, 20(4): 518–529.

    Google Scholar 

  • Szulanski, G. 1996. Exploring internal stickiness: Impediments to the transfer of best practice within the firm. Strategic Management Journal, 17(S2): 27–43.

    Google Scholar 

  • Teece, D. J. 2014. A dynamic capabilities-based entrepreneurial theory of the multinational enterprise. Journal of International Business Studies, 45(1): 8–37.

    Google Scholar 

  • Teece, D. J., Pisano, G., & Shuen, A. 1997. Dynamic capabilities and strategic management. Strategic Management Journal, 18(7): 509–533.

    Google Scholar 

  • The Economist. 2019. Slowbalisation: The future of global commerce. January 24.

  • UNCTAD. 1997. World investment report 1996 - Overview. Geneva: United Nations.

    Google Scholar 

  • UNCTAD. 2017. World investment report 2012 - Overview. Geneva: United Nations.

    Google Scholar 

  • UNSD. 2017. Standard country or area codes for statistical use (M49). United Nations Statistical Division. https://unstats.un.org/unsd/methodology/m49/. Accessed June 27, 2017.

  • Verbeke, A., Coeurderoy, R. & Matt, T. 2018. The future of international business research on corporate globalization that never was…. Journal of International Business Studies, 49(9): 1101–1112.

    Google Scholar 

  • Verbeke, A., & Forootan, M. Z. 2012. How good are multinationality–performance (M-P) empirical studies? Global Strategy Journal, 2(4): 332–344.

    Google Scholar 

  • Verbeke, A., & Kano, L. 2012. An internalization theory rationale for MNE regional strategy. Multinational Business Review, 20(2): 135–152.

    Google Scholar 

  • Vuong, Q. H. 1989. Likelihood ratio tests for model selection and non-nested hypotheses. Econometrica: Journal of the Econometric Society, 57(2): 307–333.

    Google Scholar 

  • Witt, M. A. 2019. De-globalization: Theories, predictions, and opportunities for international business research. Journal of International Business Studies, 50(7): 1053–1077.

    Google Scholar 

  • Wooldridge, J. M. 2010. Econometric analysis of cross section and panel data. Cambridge, MA: MIT press.

    Google Scholar 

  • Yayavaram, S., & Ahuja, G. 2008. Decomposability in knowledge structures and its impact on the usefulness of inventions and knowledge-base malleability. Administrative Science Quarterly, 53(2): 333–362.

    Google Scholar 

  • Yayavaram, S., & Chen, W. R. 2015. Changes in firm knowledge couplings and firm innovation performance: The moderating role of technological complexity. Strategic Management Journal, 36(3): 377-396.

    Google Scholar 

Download references

ACKNOWLEDGEMENTS

We appreciate the insightful comments and suggestions from Editor Alain Verbeke and three anonymous reviewers. We especially thank our Showcase Panelists, Yves Doz, Connie Helfat, David Teece, and Alain Verbeke at the SMS 38th Annual Conference, “Strategies in the Era of De-Globalization,” in Paris, France, whose collective works inspired this paper. The authors are also indebted to the many helpful discussions with treasured colleagues, including Rajshree Agarwal, Sharon Alvarez, Laura Cardinal, Ajai Gaur, Gwen Lee, Dan Levinthal, Chet Miller, Will Mitchell, Mahka Moeen, Ram Mudambi, Francisco Polidoro, Frank Rothaermel, Melissa Schilling, Deepak Somaya, Chris Tucci, Fred Walumbwa, Brian Wu, Margarethe Wiersema, and Ed Zajac. We dedicate this paper to Gideon Markman, the catalyst who brought us all together in Denver. Last, but certainly not least, the authors gratefully acknowledge the financial support provided by FIU CIBER and their respective institutions.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Curba Morris Lampert.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Accepted by Alain Verbeke, Editor-in-Chief, 1 December 2019. This article has been with the authors for two revisions.

Appendix

Appendix

See Table 3.

Table 3 Geographic details of our sample firms

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kim, M., Lampert, C.M. & Roy, R. Regionalization of R&D activities: (Dis)economies of interdependence and inventive performance. J Int Bus Stud 51, 1054–1075 (2020). https://doi.org/10.1057/s41267-020-00314-0

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1057/s41267-020-00314-0

Keywords

Navigation