Essential Oil Composition and Antimicrobial Activity of Santiria trimera Bark

 

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Abstract

The composition and the antimicrobial activity of the bark oil of Santiria trimera (Oliv.) Aubrév., a plant widely used by the traditional healers in S. Tomé and Príncipe, especially for wound healing, are reported for the first time. The analysis of the essential oil was carried out by GC and GC-MS. The oil contains a high content of monoterpenes, α-pinene (66.6 %) being the major constituent, followed by β-pinene (20.0 %). The essential oil was active against both bacteria and fungi strains, except Staphylococcus epidermidis and Aspergillus niger. It exhibited significant antimicrobial activity against Proteus vulgaris and Cryptococcus neoformans with MICs values of 1.11 μl/ml and lower than 0.71 μl/ml, respectively.

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Prof.ª Dra. Lígia Salgueiro

Laboratório de Farmacognosia

Faculdade de Farmácia de Coimbra

P-3000 Coimbra

Portugal

Email: ligia@ff.uc.pt

Fax: +351-23982712