Int J Angiol 2019; 28(02): 112-117
DOI: 10.1055/s-0039-1692140
Invited Article: Pulmonary Arterial Hypertension
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Novel Therapeutic Approaches of Pulmonary Arterial Hypertension

Sanjay Tyagi
1   Department of Cardiology, Maulana Azad Medical College, New Delhi, India
2   Department of Cardiology, G.B. Pant Institute of Postgraduate Medical Education and Research, New Delhi, India
,
Vishal Batra
2   Department of Cardiology, G.B. Pant Institute of Postgraduate Medical Education and Research, New Delhi, India
› Author Affiliations
Further Information

Publication History

Publication Date:
12 July 2019 (online)

Abstract

Pulmonary arterial hypertension (PAH) is an uncommon disease characterized progressive remodeling of pulmonary vasculature. Although treatment for PAH have improved in last two decades but the outcome remains fatal. Currently, the therapies for PAH target three well-established pathways the nitric oxide (NO) pathway, endothelin receptors, and prostanoids. There are multiple potential targets for development of newer drugs in PAH which requires meticulous research and clinical trials.

 
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