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J Neurol Surg Rep 2013; 74(02): 067-072
DOI: 10.1055/s-0033-1346972
Georg Thieme Verlag KG Stuttgart · New York

Metastatic Renal Cell Carcinoma to the Sinonasal Cavity: A Case Series

Aaron K. Remenschneider
1   Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, United States
,
Peter M. Sadow
2   Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States
,
Derrick T. Lin
1   Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, United States
,
Stacey T. Gray
1   Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, United States
› Author Affiliations
Further Information

Publication History

10 May 2012

10 March 2013

Publication Date:
09 May 2013 (online)

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Abstract

Objectives To describe the presentation, work-up, and management of patients with metastatic renal cell carcinoma (RCC) to the sinonasal cavity and skull base, and to describe our current treatment algorithm of endoscopic surgical resection followed by radiation therapy.

Design Retrospective review of two recent cases from our institution over a 1-year period, with a relevant review of the literature.

Setting A large regional tertiary care facility.

Participants Consecutive cases of RCC with metastases to the sinonasal cavity presenting to our institution.

Main Outcome Measures Preoperative and postoperative sinonasal outcome test (SNOT)-22 scores, duration of hospital stay, complications, and local disease control

Results Patients in this series underwent preoperative embolization followed by endoscopic resection without complication. Postoperatively they were treated with radiation therapy. They experienced improvement in their SNOT-22 scores and are currently free of local disease.

Conclusion Metastatic RCC to the sinonasal cavity can be safely treated with preoperative embolization followed by endoscopic surgical resection and radiation therapy, which can result in improvement in sinonasal quality of life and is a potential adjunct for local control of disease.

Keywords

renal cell carcinoma - quality of life - embolization - epistaxis - nasal obstruction

Presentations

This paper was presented at the North American Skull Base Society Meeting in Las Vegas, Nevada in February 2012.


 

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