Sodium Chlorite

 

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Introduction

Sodium chlorite (NaClO₂) is a highly efficient bleaching agent and oxidative disinfectant, widely applied in bleaching of textile, fiber, pulp and paper. In addition, this substance is employed to whiten sugar, starch, grease, ointment and wax. [¹]

In organic synthesis, NaClO₂ is an inexpensive and versatile reagent, which has been explored for preparations of carboxylic acids from aldehydes [²] or primary alcohols [³] , amides from imines, [4] enones from allylic and benzylic substrates, [5] epoxides from olefins [6] and γ-hydroxybutenolides from furans. [7] Moreover, this reagent has also been employed in the oxidative deprotection of 1,3-dithiane groups, [8] as oxidant and hydroxyl ion pump in osmium-catalyzed asymmetric dihydroxilation [9] as well as in the ­iodination of aromatic and heterocyclic compounds. [¹0]

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