Platinum- and Ruthenium-Catalyzed Aromatization of Enediynes via Intramolecular­ Nucleophilic Additions

 

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Abstract

Catalytic cyclization of enediynes via intramolecular nucleophilic addition was achieved with TpRuPPh₃(MeCN)₂PF₆ and platinum dichloride, giving naphthalene-fused 2,3-dihydrofurans and -pyrroles in good yields. On the basis of experimental results, the mechanism is proposed to involve nucleophilic addition to a π-alkyne intermediate, followed by alkyne insertion.

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