New Cytotoxic Alkyl Phloroglucinols from Protorhus thouvenotii

 

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Abstract

Two new cytotoxic alkylene phloroglucinols and one known compound were isolated through chromatographic separation from the methanolic extract of the dried fruits of Protorhus thouvenotii (Anacardiaceae). The compounds showed marginal in vitro cytotoxicity in the A2780 ovarian cancer cell line assay with an IC₅₀ of 11 μg/mL.

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Dr. David G. I. Kingston

Department of Chemistry

M/C 0212

Virginia Polytechnic Institute and State University

Blacksburg

Virginia 24061

USA

Phone: +1-540-231-6570

Fax: +1-540-231-3255

Email: dkingston@vt.edu