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Methods Inf Med 1994; 33(01): 116-119
DOI: 10.1055/s-0038-1634966
Original Article
Schattauer GmbH

Bonhoeffer-van der Pol Oscillator Model of the Sino-Atrial Node: A Possible Mechanism of Heart Rate Regulation

S. Sato
1   Department of Biophysical Engineering, Faculty of Engineering Science Osaka University, Japan
,
S. Doi
1   Department of Biophysical Engineering, Faculty of Engineering Science Osaka University, Japan
,
T. Nomura
1   Department of Biophysical Engineering, Faculty of Engineering Science Osaka University, Japan
› Author Affiliations
Further Information

Publication History

Publication Date:
08 February 2018 (online)

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Abstract:

A Bonhoeffer-van der Pol equation with a stable limit cycle is proposed as a model of the pacemaker in the sino-atrial node to exptain heart rate regulation. Standard tools, such as the phase transition curve in nonlinear dynamic system theory, are used to analyze the model and results are compared with other studies on experiments with dogs.

Keywords

Heart Rate Regulation - Bonhoeffervan der Pol Model - Stable Limit Cycle - Phase Transition Curve
 

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