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Methods Inf Med 2004; 43(01): 99-101
DOI: 10.1055/s-0038-1633844
Original Article
Schattauer GmbH

Nonlinear Dynamics of Respiratory Patterns during Maturation

M. Akay
1   Thayer School of Engineering, Dartmouth College, Hanover, NH, USA
,
M. Sekine
1   Thayer School of Engineering, Dartmouth College, Hanover, NH, USA
,
K. L. Moodie
2   Department of Surgery, Dartmouth Medical School, Lebanon, NH, USA
› Author Affiliations
Further Information

Publication History

Publication Date:
07 February 2018 (online)

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Summary

Objectives: In this paper, we quantify the fractal scaling characteristics of phrenic neurograms during eupnea in piglets, the output of the respiratory neural network that accompany maturation We also attempt to investigate whether the fractal properties are altered with maturation.

Methods: The phrenic neurogram in piglets was recorded from the C5 phrenic nerve during eupnea at four postnatal ages; the 3-6 days, the 7-14 days, 15-21 days and the 26-31 days age groups and analyzed using the maximum likelihood estimator (MLE).

Results: Our results suggest that the mean fractal measures over a recording of five consecutive breaths during eupnea for each piglet in each group were higher during the first 6 days and slightly decreased for the 7-14 days and significantly decreased for the 15-21 days and significantly increased for subsequent maturation (the 26-31 days old group).

Conclusions: We suggest that there is a significant alteration in the fractal organization in piglet respiratory patterns during maturation and a decrease in the fractal value is unique to the15-21 days old group.

Keywords

Fractals - maturation - phrenic neurograms - eupnea
 

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