Two Pairs of Epimeric Indole Alkaloids from Catharanthus roseus

 

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Abstract

Two pairs of epimeric indole alkaloids (1–4) with a chlorine atom were isolated from the aerial part of Catharanthus roseus. Their structures were established on the basis of the spectroscopic data including UV, IR, HRESIMS, NMR, and X-ray diffraction analyses. The cytotoxic activities of 1–4 against the HepG2 cell line were evaluated.

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Prof. Dr. Wen-Cai Ye

Institute of Traditional Chinese Medicine and Natural Products
College of Pharmacy, Jinan University

No. 601 Huangpu Road West

Guangzhou 510632

P. R. China

Phone: +86 20 85 22 15 59

Fax: +86 20 85 22 15 59

Email: chywc@yahoo.com.cn

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