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Planta Med 2010; 76(9): 909-915
DOI: 10.1055/s-0029-1240842
Natural Product Chemistry
Original Papers
© Georg Thieme Verlag KG Stuttgart · New York

Perisesaccharides A–E, New Oligosaccharides from the Root Barks of Periploca sepium

Lei Wang1 , 2 , Zhi-Qi Yin1 , Ying Wang2 , 3 , Xiao-Qi Zhang2 , 3 , Yao-Lan Li2 , 3 , Wen-Cai Ye1 , 2 , 3
  • 1Department of Phytochemistry, China Pharmaceutical University, Nanjing, P. R. China
  • 2Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou, P. R. China
  • 3Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, P. R. China
Further Information

Publication History

received October 14, 2009 revised Dec. 31, 2009

accepted January 6, 2010

Publication Date:
08 February 2010 (online)

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Abstract

Five new oligosaccharides, named perisesaccharides A–E (1–5), were isolated from the root barks of Periploca sepium. Their structures were elucidated by NMR and HRESIMS data. The absolute configurations of these compounds were determined by a combination of X‐ray diffraction analysis, modified Mosher's method, circular dichroism spectroscopy, and acid hydrolysis. The boat conformation of oleandronic acid δ-lactone was reported for the first time.

Key words

Asclepiadaceae - Periploca sepium - oligosaccharid - perisesaccharides A–E - oleandronic acid δ‐lactone

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Prof. Dr. Wen-Cai Ye

Institute of Traditional Chinese Medicine and Natural Products
Jinan University

601 West Huangpu Avenue

510 632 Guangzhou

P. R. China

Phone: + 86 20 85 22 15 59

Fax: + 86 20 85 22 15 59

Email: chywc@yahoo.com.cn

Dr. Zhi-Qi Yin

Department of Phytochemistry
China Pharmaceutical University

24 Tongjia Lane

210009 Nanjing

P. R. China

Phone: + 86 25 86 18 53 71

Fax: + 86 25 85 30 15 28

Email: chyzq2005@126.com

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