Original ArticlesThe utility of epithelial membrane antigen and vimentin in the diagnosis of chromophobe renal cell carcinoma
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Immunohistochemistry for the diagnosis of renal epithelial neoplasms
2022, Seminars in Diagnostic PathologyCitation Excerpt :This combination of features is usually sufficient to make the diagnosis without IHC or molecular studies.119 However, diffuse keratin 7 (Fig. 7B) and KIT (Fig. 7C) labeling are often present in chromophobe RCC, a combination that is very unusual in other type of tumors with clear cell cytology75, 119Vimentin is consistently negative in chromophobe RCC, in contrast with clear cell RCC.120 Less utilized biomarkers are kidney specific cadherin and parvalbumin.121
Neoplasms of the Kidney
2020, Urologic Surgical PathologyBroad-spectrum immunohistochemical epithelial markers: A review
2013, Human PathologyEpithelial Neoplasms of the Renal Cortex
2013, Practical Renal Pathology: A Diagnostic ApproachPrognostic factors and predictive models in renal cell carcinoma: A contemporary review
2011, European UrologyCitation Excerpt :A cytoplasmic intermediate filament, vimentin is not usually expressed in epithelial cells (Fig. 1). Vimentin expression is common in clear cell (26–51%) and papillary RCC (61%) [120–124]. Others found low frequency of vimentin staining in clear cell RCC [125].
Neoplasms of the kidney
2008, Urologic Surgical Pathology: Second Edition
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