SCHEDULED MAINTENANCE
A focus on how latent “codons” are unravelled in synthetic copolymers
Christopher
Barner-Kowollik 
*ab
and
Bryan T.
Tuten
*a
*ab
and
Bryan T.
Tuten
*a
Abstract
We contextualize and highlight an innovative methodology for copolymer analysis introduced by Hibi et al. in Chemical Science (Y. Hibi, S. Uesaka and M. Naito, Chem. Sci., 2023, https://doi.org/10.1039/D2SC06974A). The authors introduce an advanced mass spectrometric method driven by a learning algorithm, termed ‘reference-free quantitative mass spectrometry’ (RQMS) for decoding sequences of copolymers in real time, including as a function of reaction progress. We highlight potential future implications and applications of the RQMS technique, as well as look forward to where else RQMS could be utilized within the soft matter materials space.
- This article is part of the themed collections: Chemistry of polymers - Chemical Science symposium collection and Chemical Science Focus Articles
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