Issue 37, 2021
From the journal:

Organic & Biomolecular Chemistry

Visible light-induced C–C bond cleavage in a multicomponent reaction cascade allowing acylations of sulfoximines with ketones†

Yongliang Tu,a   Duo Zhang,a   Peng Shi,a   Chenyang Wang, ORCID logo a   Ding Maa  and  Carsten Bolm ORCID logo *a  

* Corresponding authors

a Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074 Aachen, Germany
E-mail: carsten.bolm@oc.rwth-aachen.de
Web: http://bolm.oc.rwth-aachen.de

Abstract

Visible light induces C–C-bond cleavage reactions of ketones, which can be utilized for N-acylations of sulfoximines. No (photo)catalyst is required, and the reactions occur at ambient temperature in air. The substrate scope is broad for both ketones and sulfoximines. For converting NH-sulfoximines, the presence of NBS is essential.

Graphical abstract: Visible light-induced C–C bond cleavage in a multicomponent reaction cascade allowing acylations of sulfoximines with ketones

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Article information

DOI
https://doi.org/10.1039/D1OB01411K
Article type
Paper
Submitted
20 Jul 2021
Accepted
18 Aug 2021
First published
18 Aug 2021

Org. Biomol. Chem., 2021,19, 8096-8101

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Visible light-induced C–C bond cleavage in a multicomponent reaction cascade allowing acylations of sulfoximines with ketones

Y. Tu, D. Zhang, P. Shi, C. Wang, D. Ma and C. Bolm, Org. Biomol. Chem., 2021, 19, 8096 DOI: 10.1039/D1OB01411K

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