SCHEDULED MAINTENANCE
Constructing fused N-heterocycles from unprotected mesoionic N-heterocyclic olefins and organic azides via diazo transfer†
Qiuming
Liang, 
a
Datong
Song
*a
a
Datong
Song
*a
Abstract
Mesoionic N-heterocyclic olefins (mNHOs) were first reported last year and their reactivity remains largely unexplored. Herein we report the reaction of unprotected mNHOs and organic azides as a novel synthetic route to a variety of pyrazolo[3,4-d][1,2,3]triazoles, an important structural motif in drug candidates and energetic materials. The only byproduct aniline can be easily recycled and converted back to the starting organic azide, in compliance with the green chemistry principle. The reaction mechanism has been explored through experimental and computational studies.
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