Issue 28, 2019
From the journal:

Organic & Biomolecular Chemistry

Fe-Catalyzed enaminone synthesis from ketones and amines†

Wenfeng Wu,‡a   Zhuxian Wang,‡a   Qun Shen,a   Qiang Liu*a  and  Huoji Chen ORCID logo *a  

* Corresponding authors

a School of Traditional Chinese Medicine, Southern Medical University, 1023 South Shatai Road, Baiyun District, Guangzhou 510515, P. R. China
E-mail: gzlq2002@163.com, chenhuoji2005@126.com

Abstract

We have developed an iron-catalyzed direct olefination for enaminone synthesis, with saturated ketones as a source of olefins. This direct ketone β-functionalization reaction has readily available starting materials and a wide range of substrates and requires mild reaction conditions.

Graphical abstract: Fe-Catalyzed enaminone synthesis from ketones and amines

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Article information

DOI
https://doi.org/10.1039/C9OB01137D
Article type
Communication
Submitted
15 May 2019
Accepted
24 Jun 2019
First published
24 Jun 2019

Org. Biomol. Chem., 2019,17, 6753-6756

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Fe-Catalyzed enaminone synthesis from ketones and amines

W. Wu, Z. Wang, Q. Shen, Q. Liu and H. Chen, Org. Biomol. Chem., 2019, 17, 6753 DOI: 10.1039/C9OB01137D

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