Issue 85, 2019
From the journal:

Chemical Communications

Corroles and corrole/transferrin nanoconjugates as candidates for sonodynamic therapy†

Vinay Kumar Sharma, ORCID logo a   Atif Mahammed,a   Matan Soll,a   Boris Tumanskiia  and  Zeev Gross ORCID logo *a  

* Corresponding authors

a Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa 32000, Israel
E-mail: chr10zg@technion.ac.il

Abstract

We report the utility of water-soluble corroles and also protein-coated nanoparticles (NPs) of lipophilic corroles as potent candidates for sonodynamic therapy (SDT), through the detection and quantification of the singlet oxygen that is produced by the ultrasonic irradiation of their aqueous solutions. Preliminary results on a cancer cell line provide evidence for the true utility of the NPs for SDT.

Graphical abstract: Corroles and corrole/transferrin nanoconjugates as candidates for sonodynamic therapy

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Article information

DOI
https://doi.org/10.1039/C9CC06494J
Article type
Communication
Submitted
22 Aug 2019
Accepted
13 Sep 2019
First published
27 Sep 2019

Chem. Commun., 2019,55, 12789-12792

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Corroles and corrole/transferrin nanoconjugates as candidates for sonodynamic therapy

V. K. Sharma, A. Mahammed, M. Soll, B. Tumanskii and Z. Gross, Chem. Commun., 2019, 55, 12789 DOI: 10.1039/C9CC06494J

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