Superwettable nanodendritic gold substrates for direct miRNA SERS detection

Yongchao Song; Tailin Xu; Li-Ping Xu; Xueji Zhang

doi:10.1039/C8NR07348A

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Superwettable nanodendritic gold substrates for direct miRNA SERS detection†

Yongchao Song,^a Tailin Xu,

*^a Li-Ping Xu*^a and Xueji Zhang*^a

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* Corresponding authors

^a Research Center for Bioengineering and Sensing Technology, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, P. R. China
E-mail: xutailin@ustb.edu.cn, xuliping@ustb.edu.cn, zhangxueji@ustb.edu.cn

Abstract

By combining a superwettable interface with a nanodendritic gold structure, we have fabricated a superwettable nanodendritic gold substrate for direct SERS detection of multiple concentrations of miRNAs. The nanodendritic gold substrate provides numerous hotspots for Raman signal enhancement, and the superwettable interface ensures the immobilization of droplets in superhydrophilic microwells, which hold great potentials for applications in disease diagnostics.

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Article information

DOI: https://doi.org/10.1039/C8NR07348A
Article type: Communication
Submitted: 10 Sep 2018
Accepted: 24 Oct 2018
First published: 25 Oct 2018

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Nanoscale, 2018,10, 20990-20994

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Superwettable nanodendritic gold substrates for direct miRNA SERS detection

Y. Song, T. Xu, L. Xu and X. Zhang, Nanoscale, 2018, 10, 20990 DOI: 10.1039/C8NR07348A

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Superwettable nanodendritic gold substrates for direct miRNA SERS detection†

Abstract

Supplementary files

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Superwettable nanodendritic gold substrates for direct miRNA SERS detection

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