Issue 66, 2018
From the journal:

Chemical Communications

Switching the subcellular organelle targeting of atomically precise gold nanoclusters by modifying the capping ligand†

Ying Yang, ORCID logo a   Shuxin Wang, ORCID logo *a   Shuang Chen,a   Yuhua Shen ORCID logo *a  and  Manzhou Zhu ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Collaborative Innovation Center of Modern Bio-manufacture, Center for Atomic Engineering of Advanced Materials and Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Anhui University, Hefei 230601, P. R. China
E-mail: ixing@ahu.edu.cn, s_yuhua@163.com, zmz@ahu.edu.cn

Abstract

Here, we have achieved the target switching fluorescence imaging and photodynamic activity of hydrosoluble AuNCs from lysosomes to mitochondria through ligand exchange. This work unveils the ligand-regulated subcellular distribution of AuNCs by which new strategies to improve their bio-applications such as precise nanotheranostics could be realized.

Graphical abstract: Switching the subcellular organelle targeting of atomically precise gold nanoclusters by modifying the capping ligand

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Article information

DOI
https://doi.org/10.1039/C8CC04474K
Article type
Communication
Submitted
05 Jun 2018
Accepted
22 Jul 2018
First published
23 Jul 2018

Chem. Commun., 2018,54, 9222-9225

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Switching the subcellular organelle targeting of atomically precise gold nanoclusters by modifying the capping ligand

Y. Yang, S. Wang, S. Chen, Y. Shen and M. Zhu, Chem. Commun., 2018, 54, 9222 DOI: 10.1039/C8CC04474K

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