Issue 8, 2019
From the journal:

Analyst

Molecular evidence of a toxic effect on a biofilm and its matrix†

Yuanzhao Ding, ORCID logo ab   Yufan Zhou, ORCID logo c   Juan Yao, ORCID logo a   Yijia Xiong, ORCID logo d   Zihua Zhu ORCID logo *c  and  Xiao-Ying Yu ORCID logo *a  

* Corresponding authors

a Earth and Biological Sciences Directorate, Pacific Northwest National Laboratory, Richland, Washington 99354, USA
E-mail: xiaoying.yu@pnnl.gov

b Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University, Singapore

c Environmental and Molecular Science Laboratory, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
E-mail: zihua.zhu@pnnl.gov

d College of Osteopathic Medicine of the Pacific-Northwest, Western University of Health Sciences, Lebanon, Oregon 97355, USA

Abstract

Shewanella oneidensis MR-1 wild-type and a hyper-adhesive mutant CP2-1-S1 are used as model organisms and Cr(VI) is selected as a toxic chemical to study biofilm and toxic chemical interactions. Biofilms are cultured in a microfluidic device for in situ time-of-flight secondary ion mass spectrometry imaging. This approach is viable for studying biofilms’ responses to antimicrobial resistance.

Graphical abstract: Molecular evidence of a toxic effect on a biofilm and its matrix

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Article information

DOI
https://doi.org/10.1039/C8AN02512F
Article type
Communication
Submitted
29 Dec 2018
Accepted
26 Jan 2019
First published
29 Jan 2019

Analyst, 2019,144, 2498-2503

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Molecular evidence of a toxic effect on a biofilm and its matrix

Y. Ding, Y. Zhou, J. Yao, Y. Xiong, Z. Zhu and X. Yu, Analyst, 2019, 144, 2498 DOI: 10.1039/C8AN02512F

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