Issue 9, 2018

In situ fluorescence activation of DNA–silver nanoclusters as a label-free and general strategy for cell nucleus imaging

Abstract

A facile, general and turn-on nucleus imaging strategy was first developed based on in situ fluorescence activation of C-rich dark silver nanoclusters by G-rich telomeres. After a simple incubation without washing, nanoclusters could selectively stain the nucleus with intense red luminescence, which was confirmed using fixed/living cells and several cell lines.

Graphical abstract: In situ fluorescence activation of DNA–silver nanoclusters as a label-free and general strategy for cell nucleus imaging

Supplementary files

Article information

Article type
Communication
Submitted
25 Oct 2017
Accepted
02 Jan 2018
First published
02 Jan 2018

Chem. Commun., 2018,54, 1089-1092

In situ fluorescence activation of DNA–silver nanoclusters as a label-free and general strategy for cell nucleus imaging

D. Li, Z. Qiao, Y. Yu, J. Tang, X. He, H. Shi, X. Ye, Y. Lei and K. Wang, Chem. Commun., 2018, 54, 1089 DOI: 10.1039/C7CC08228B

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