SCHEDULED MAINTENANCE
An N-heterocyclic carbene iridium catalyst with metal-centered chirality for enantioselective transfer hydrogenation of imines†
Eric
Meggers 
ab
and
Lei
Gong
*a
ab
and
Lei
Gong
*a
Abstract
A cyclometalating N-heterocyclic carbene iridium complex featuring metal-centered chirality was designed and used for the asymmetric transfer hydrogenation (ATH) of imines. Four strongly σ-donating carbon-based substituents (2 carbenes and 2 phenyl moieties), a chirality transfer directly from the stereogenic metal center to the C![[double bond, length as m-dash]](https://www.rsc.org/images/entities/char_e001.gif)
N bond of substrates, as well as a restriction of catalyst deactivation by steric demanding substituents, render the new complex one of the most efficient catalysts for ATH of cyclic N-sulfonylimines (down to 0.01 mol% cat., 24 examples, 94–98% ee).
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