Issue 1, 2018

SPIONs for cell labelling and tracking using MRI: magnetite or maghemite?

Abstract

Although there is extensive literature covering the biomedical applications of superparamagnetic iron oxide nanoparticles (SPIONs), the phase of the iron oxide core used is not often taken into account when cell labelling and tracking studies for regenerative medicine are considered. Here, we use a co-precipitation reaction to synthesise particles of both magnetite- (Fe3O4) and maghemite- (γ-Fe2O3) based cores and consider whether the extra synthesis step to make maghemite based particles is advantageous for cell tracking.

Graphical abstract: SPIONs for cell labelling and tracking using MRI: magnetite or maghemite?

Supplementary files

Article information

Article type
Communication
Submitted
13 Jun 2017
Accepted
23 Nov 2017
First published
23 Nov 2017
This article is Open Access
Creative Commons BY license

Biomater. Sci., 2018,6, 101-106

SPIONs for cell labelling and tracking using MRI: magnetite or maghemite?

M. Barrow, A. Taylor, A. M. Fuentes-Caparrós, J. Sharkey, L. M. Daniels, P. Mandal, B. K. Park, P. Murray, M. J. Rosseinsky and D. J. Adams, Biomater. Sci., 2018, 6, 101 DOI: 10.1039/C7BM00515F

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