Issue 10, 2016

PtCo bimetallic nanoparticles with high oxidase-like catalytic activity and their applications for magnetic-enhanced colorimetric biosensing

Abstract

A novel magnetic-enhanced colorimetric assay was constructed based on aptamer conjugated PtCo bimetallic nanoparticles (NPs) with high oxidase-like catalytic activity, high water solubility, low cell toxicity, and superparamagnetic properties. It was found that the incorporation of magnetic metal Co atoms into NPs could not only be facilitated for magnetic separation, but also resulted in the significantly improved oxidase-like catalytic activity of the nanoparticles for cancer-cell detection without the destructive H2O2. The present work demonstrates a general strategy for the design of multifunctional materials based on bimetallic nanoparticles for different applications, such as biosensors, nanocatalysts and nanomedicine.

Graphical abstract: PtCo bimetallic nanoparticles with high oxidase-like catalytic activity and their applications for magnetic-enhanced colorimetric biosensing

Supplementary files

Article information

Article type
Paper
Submitted
02 Oct 2015
Accepted
06 Feb 2016
First published
22 Feb 2016

J. Mater. Chem. B, 2016,4, 1869-1877

PtCo bimetallic nanoparticles with high oxidase-like catalytic activity and their applications for magnetic-enhanced colorimetric biosensing

S. Cai, C. Qi, Y. Li, Q. Han, R. Yang and C. Wang, J. Mater. Chem. B, 2016, 4, 1869 DOI: 10.1039/C5TB02052B

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