Issue 109, 2015
From the journal:

RSC Advances

In vitro and in vivo applications of alginate/iron oxide nanocomposites for theranostic molecular imaging in a brain tumor model†

Chia-Hao Sua  and  Fong-Yu Cheng*b  

* Corresponding authors

a Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Department of Biomedical Imaging, Kaohsiung 833, and Radiological Sciences, National Yang Ming University, Taipei 112, Taiwan

b Institute of Oral Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 1 University Road, Tainan City 701, Taiwan
E-mail: FYCheng@mail.ncku.edu.tw

Abstract

Nanocomposites composed of highly biocompatible and safe alginate and iron oxide nanoparticles have been employed to encapsulate doxorubicine for brain tumor therapy. The antitumor activity of nanocomposites was demonstrated using in vitro and in vivo tests. The results significantly indicated that the nanocomposites had great safety and potential for brain tumor therapy.

Graphical abstract: In vitro and in vivo applications of alginate/iron oxide nanocomposites for theranostic molecular imaging in a brain tumor model

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Article information

DOI
https://doi.org/10.1039/C5RA20723A
Article type
Communication
Submitted
07 Oct 2015
Accepted
15 Oct 2015
First published
15 Oct 2015

RSC Adv., 2015,5, 90061-90064

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In vitro and in vivo applications of alginate/iron oxide nanocomposites for theranostic molecular imaging in a brain tumor model

C. Su and F. Cheng, RSC Adv., 2015, 5, 90061 DOI: 10.1039/C5RA20723A

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