Issue 18, 2016
From the journal:

Chemical Communications

Enzymatic activatable self-assembled peptide nanowire for targeted therapy and fluorescence imaging of tumors†

Ying Tang,a   Zhan Wu,*a   Chong-Hua Zhang,a   Xiao-Li Zhanga  and  Jian-Hui Jiang*a  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China
E-mail: jianhuijiang@hnu.edu.cn, zhanwu@hnu.edu.cn
Fax: +86-731-88822872
Tel: +86-731-88822577

Abstract

We developed novel activatable probe using self-assembled peptide nanowires with low affinity and toxicity to tumor cells in the absence of matrix metalloproteinase that showed activated high affinity and toxicity and provided a highly selective and efficient platform for targeted therapy and tumor imaging.

Graphical abstract: Enzymatic activatable self-assembled peptide nanowire for targeted therapy and fluorescence imaging of tumors

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Article information

DOI
https://doi.org/10.1039/C5CC10591A
Article type
Communication
Submitted
27 Dec 2015
Accepted
25 Jan 2016
First published
25 Jan 2016

Chem. Commun., 2016,52, 3631-3634

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Enzymatic activatable self-assembled peptide nanowire for targeted therapy and fluorescence imaging of tumors

Y. Tang, Z. Wu, C. Zhang, X. Zhang and J. Jiang, Chem. Commun., 2016, 52, 3631 DOI: 10.1039/C5CC10591A

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