Issue 3, 2016

Engineering β-sheet peptide assemblies for biomedical applications

Abstract

Hydrogels have been widely studied in various biomedical applications, such as tissue engineering, cell culture, immunotherapy and vaccines, and drug delivery. Peptide-based nanofibers represent a promising new strategy for current drug delivery approaches and cell carriers for tissue engineering. This review focuses on the recent advances in the use of self-assembling engineered β-sheet peptide assemblies for biomedical applications. The applications of peptide nanofibers in biomedical fields, such as drug delivery, tissue engineering, immunotherapy, and vaccines, are highlighted. The current challenges and future perspectives for self-assembling peptide nanofibers in biomedical applications are discussed.

Graphical abstract: Engineering β-sheet peptide assemblies for biomedical applications

Article information

Article type
Review Article
Submitted
21 Oct 2015
Accepted
03 Dec 2015
First published
24 Dec 2015

Biomater. Sci., 2016,4, 365-374

Engineering β-sheet peptide assemblies for biomedical applications

Z. Yu, Z. Cai, Q. Chen, M. Liu, L. Ye, J. Ren, W. Liao and S. Liu, Biomater. Sci., 2016, 4, 365 DOI: 10.1039/C5BM00472A

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