Issue 45, 2014
From the journal:

RSC Advances

Microfluidic fabrication of multiaxial microvessels via hydrodynamic shaping†

Michael A. Daniele,a   Kathryn Radom,b   Frances S. Liglerc  and  André A. Adams*a  

* Corresponding authors

a Center for Bio/Molecular Science and Engineering, U.S. Naval Research Laboratory, 4555 Overlook Ave. SW, Washington, D.C. 20375, USA
E-mail: andre.adams@nrl.navy.mil

b Naval Research Enterprise Internship Program, U.S. Naval Research Laboratory, 4555 Overlook Ave. SW, Washington, D.C. 20375, USA

c Department of Biomedical Engineering, University of North Carolina Chapel Hill and North Carolina State University, Raleigh, North Carolina 27695, USA

Abstract

A microfluidic fiber fabrication device was developed to prepare multiaxial microvessels with defined architecture and material constituency. Hydrodynamic focusing using passive wall structures directed biologically relevant macromer solutions into coaxial flow patterns, which were subsequently solidified via photopolymerization. Solid, coaxial, and triaxial microfibers as well as microtubes were generated from the multiaxial flows composed of both synthetic macromers and biomacromolecules.

Graphical abstract: Microfluidic fabrication of multiaxial microvessels via hydrodynamic shaping

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Article information

DOI
https://doi.org/10.1039/C4RA03667K
Article type
Paper
Submitted
22 Apr 2014
Accepted
11 May 2014
First published
12 May 2014

RSC Adv., 2014,4, 23440-23446

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Microfluidic fabrication of multiaxial microvessels via hydrodynamic shaping

M. A. Daniele, K. Radom, F. S. Ligler and A. A. Adams, RSC Adv., 2014, 4, 23440 DOI: 10.1039/C4RA03667K

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