Issue 24, 2015
From the journal:

Physical Chemistry Chemical Physics

Protein synthesis in artificial cells: using compartmentalisation for spatial organisation in vesicle bioreactors†

Yuval Elani,ab   Robert V. Lawab  and  Oscar Ces*ab  

* Corresponding authors

a Department of Chemistry, Imperial College London, Exhibition Road, UK
E-mail: o.ces@imperial.ac.uk

b Institute of Chemical Biology, Imperial College London, Exhibition Road, UK

Abstract

Whereas spatial organisation of function is ubiquitous in biology, it has been lacking in artificial cells. We rectify this by using multi-compartment vesicles as chassis for artificial cells, allowing distinct biological processes to be isolated in space. This is demonstrated by in vitro synthesis of two proteins in predefined vesicle regions.

Graphical abstract: Protein synthesis in artificial cells: using compartmentalisation for spatial organisation in vesicle bioreactors

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Article information

DOI
https://doi.org/10.1039/C4CP05933F
Article type
Communication
Submitted
17 Dec 2014
Accepted
17 Mar 2015
First published
01 May 2015
This article is Open Access
Creative Commons BY license

Phys. Chem. Chem. Phys., 2015,17, 15534-15537

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Protein synthesis in artificial cells: using compartmentalisation for spatial organisation in vesicle bioreactors

Y. Elani, R. V. Law and O. Ces, Phys. Chem. Chem. Phys., 2015, 17, 15534 DOI: 10.1039/C4CP05933F

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