Issue 80, 2014
From the journal:

Chemical Communications

A novel graphene oxide based fluorescent nanosensing strategy with hybridization chain reaction signal amplification for highly sensitive biothiol detection†

Jia Ge,a   Zhi-Mei Huang,a   Qiang Xi,a   Ru-Qin Yu,a   Jian-Hui Jianga  and  Xia Chu*a  

* Corresponding authors

a State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, P. R. China
E-mail: xiachu@hnu.edu.cn
Fax: +86-731-88821916
Tel: +86-731-88821916

Abstract

A novel fluorescent nanosensor has been developed for detecting biothiols including cysteine and glutathione using graphene oxide based hairpin DNA-selective fluorescence quenching and thymine–Hg(II)–thymine coordination-controlled hybridization chain reaction, which provides a simple but the most sensitive platform for biothiol assays.

Graphical abstract: A novel graphene oxide based fluorescent nanosensing strategy with hybridization chain reaction signal amplification for highly sensitive biothiol detection

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Article information

DOI
https://doi.org/10.1039/C4CC05309E
Article type
Communication
Submitted
10 Jul 2014
Accepted
12 Aug 2014
First published
15 Aug 2014

Chem. Commun., 2014,50, 11879-11882

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A novel graphene oxide based fluorescent nanosensing strategy with hybridization chain reaction signal amplification for highly sensitive biothiol detection

J. Ge, Z. Huang, Q. Xi, R. Yu, J. Jiang and X. Chu, Chem. Commun., 2014, 50, 11879 DOI: 10.1039/C4CC05309E

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