Issue 95, 2014
From the journal:

Chemical Communications

Micropatterning of hydrophilic polyacrylamide brushes to resist cell adhesion but promote protein retention†

Jianwen Hou,ab   Qiang Shi,*a   Wei Ye,ab   Paola Stagnaroc  and  Jinghua Yin*a  

* Corresponding authors

a State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, P. R. China
E-mail: shiqiang@ciac.ac.cn, yinjh@ciac.ac.cn

b University of the Chinese Academy of Sciences, Beijing 100039, P. R. China

c Istituto per lo Studio delle Macromolecole, UOS Genova, Via De Marini 6, Genova, Italy

Abstract

Contrary to a prevailing concept on protein adsorption and cell adhesion, novel micropatterned polyacrylamide (PAAm) brushes that can resist cell adhesion but promote protein retention are created through patterning of ATRP initiators and surface-initiated ATRP on a polymer substrate.

Graphical abstract: Micropatterning of hydrophilic polyacrylamide brushes to resist cell adhesion but promote protein retention

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Article information

DOI
https://doi.org/10.1039/C4CC03994G
Article type
Communication
Submitted
25 May 2014
Accepted
09 Oct 2014
First published
09 Oct 2014

Chem. Commun., 2014,50, 14975-14978

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Micropatterning of hydrophilic polyacrylamide brushes to resist cell adhesion but promote protein retention

J. Hou, Q. Shi, W. Ye, P. Stagnaro and J. Yin, Chem. Commun., 2014, 50, 14975 DOI: 10.1039/C4CC03994G

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