Issue 42, 2013

Synthesis and C2-functionalization of indoles with allylic acetates under rhodium catalysis

Abstract

Tandem rhodium-catalyzed oxidative allylation and annulation of acetanilides with allyl acetate to afford the corresponding indoles are described. In addition, the site-selective C2 allylation, crotylation and prenylation of indoles using allylic acetates under rhodium catalysis are reported.

Graphical abstract: Synthesis and C2-functionalization of indoles with allylic acetates under rhodium catalysis

Supplementary files

Article information

Article type
Paper
Submitted
27 Aug 2013
Accepted
17 Sep 2013
First published
17 Sep 2013

Org. Biomol. Chem., 2013,11, 7427-7434

Synthesis and C2-functionalization of indoles with allylic acetates under rhodium catalysis

M. Kim, J. Park, S. Sharma, S. Han, S. H. Han, J. H. Kwak, Y. H. Jung and I. S. Kim, Org. Biomol. Chem., 2013, 11, 7427 DOI: 10.1039/C3OB41828F

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