Issue 14, 2014

Palladium-catalyzed double C–H activation: one-pot synthesis of benzo[c]pyrazolo[1,2-a]cinnolin-1-ones from 5-pyrazolones and aryl iodides

Abstract

A palladium-catalyzed dual C–H activation to construct C–C/C–N bonds for one-pot synthesis of benzo[c]pyrazolo[1,2-a]cinnolin-1-ones is successfully developed. This approach involves using a pyrazolone moiety as an internal directing group for C–H activation, and provides a flexible strategy to access this polycyclic skeleton.

Graphical abstract: Palladium-catalyzed double C–H activation: one-pot synthesis of benzo[c]pyrazolo[1,2-a]cinnolin-1-ones from 5-pyrazolones and aryl iodides

Supplementary files

Article information

Article type
Communication
Submitted
17 Oct 2013
Accepted
05 Dec 2013
First published
06 Dec 2013

Chem. Commun., 2014,50, 1682-1684

Author version available

Palladium-catalyzed double C–H activation: one-pot synthesis of benzo[c]pyrazolo[1,2-a]cinnolin-1-ones from 5-pyrazolones and aryl iodides

Z. Fan, K. Wu, L. Xing, Q. Yao and A. Zhang, Chem. Commun., 2014, 50, 1682 DOI: 10.1039/C3CC47989G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements