Issue 80, 2013
From the journal:

Chemical Communications

A highly sensitive near-infrared fluorescent probe for cysteine and homocysteine in living cells†

Fanpeng Kong,a   Renpu Liu,a   Ranran Chu,a   Xu Wang,a   Kehua Xu*a  and  Bo Tang*a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Ministry of Education, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P.R. China
E-mail: tangb@sdnu.edu.cn
Fax: +86-0531-86180017
Tel: +86-0531-86180010

Abstract

A near-infrared fluorescent probe (Cy–O–CHO) for the detection of endogenous Cys/Hcy in living cells was designed and synthesized. Cy–O–CHO exhibited high sensitivity and good selectivity to Cys/Hcy under physiological conditions with a detection limit of 7.9 nM for Cys.

Graphical abstract: A highly sensitive near-infrared fluorescent probe for cysteine and homocysteine in living cells

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Article information

DOI
https://doi.org/10.1039/C3CC45519J
Article type
Communication
Submitted
21 Jul 2013
Accepted
07 Aug 2013
First published
07 Aug 2013

Chem. Commun., 2013,49, 9176-9178

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A highly sensitive near-infrared fluorescent probe for cysteine and homocysteine in living cells

F. Kong, R. Liu, R. Chu, X. Wang, K. Xu and B. Tang, Chem. Commun., 2013, 49, 9176 DOI: 10.1039/C3CC45519J

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