Issue 91, 2013

“Clickable” LNA/DNA probes for fluorescence sensing of nucleic acids and autoimmune antibodies

Abstract

Herein we describe fluorescent oligonucleotides prepared by click chemistry between novel alkyne-modified locked nucleic acid (LNA) strands and a series of fluorescent azides for homogeneous (all-in-solution) detection of nucleic acids and autoimmune antibodies.

Graphical abstract: “Clickable” LNA/DNA probes for fluorescence sensing of nucleic acids and autoimmune antibodies

Supplementary files

Article information

Article type
Communication
Submitted
20 Jul 2013
Accepted
19 Sep 2013
First published
27 Sep 2013
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2013,49, 10751-10753

“Clickable” LNA/DNA probes for fluorescence sensing of nucleic acids and autoimmune antibodies

A. S. Jørgensen, P. Gupta, J. Wengel and I. K. Astakhova, Chem. Commun., 2013, 49, 10751 DOI: 10.1039/C3CC45507F

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