Issue 86, 2013
From the journal:

Chemical Communications

Electrophile induced branching cascade: a powerful approach to access various molecular scaffolds and their exploration as novel anti-mycobacterial agents†

Nitin T. Patil,‡*a   Ashok Konala,a   Sudha Sravanti,b   Ashita Singh,b   Ramesh Ummannib  and  Balasubramanian Sridharc  

* Corresponding authors

a CSIR – Indian Institute of Chemical Technology, Hyderabad – 500 007, India

b Centre for Chemical Biology, CSIR – Indian Institute of Chemical Technology, Hyderabad – 500 007, India

c Laboratory of X-Ray Crystallography CSIR –Indian Institute of Chemical Technology, Hyderabad – 500 007, India

Abstract

Herein we report on the Electrophile Induced Branching Cascade (EIBC), a new technique to produce a variety of biologically important molecular scaffolds. Some compounds exhibit excellent activities against Mycobacterium smegmatis.

Graphical abstract: Electrophile induced branching cascade: a powerful approach to access various molecular scaffolds and their exploration as novel anti-mycobacterial agents

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Article information

DOI
https://doi.org/10.1039/C3CC45289A
Article type
Communication
Submitted
16 Jul 2013
Accepted
30 Aug 2013
First published
02 Sep 2013

Chem. Commun., 2013,49, 10109-10111

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Electrophile induced branching cascade: a powerful approach to access various molecular scaffolds and their exploration as novel anti-mycobacterial agents

N. T. Patil, A. Konala, S. Sravanti, A. Singh, R. Ummanni and B. Sridhar, Chem. Commun., 2013, 49, 10109 DOI: 10.1039/C3CC45289A

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