Issue 35, 2013
From the journal:

Chemical Communications

A sensitive SERS assay of l-histidinevia a DNAzyme-activated target recycling cascade amplification strategy†

Sujuan Ye,a   Yuanyuan Guo,a   Jie Xiaoa  and  Shusheng Zhang*a  

* Corresponding authors

a Key Laboratory of Biochemical Analysis, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China
E-mail: shushzhang@126.com
Fax: +86 532 84022750
Tel: +86 532 84022750

Abstract

A novel surface-enhanced Raman scattering (SERS) method is demonstrated to detect L-histidine based on DNAzyme which can specifically recognize L-histidine. Through a target recycling cascade amplification strategy, the DNAzyme-based SERS sensing system affords very high sensitivity for L-histidine with a detection limit of 0.56 nM.

Graphical abstract: A sensitive SERS assay of l-histidine via a DNAzyme-activated target recycling cascade amplification strategy

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Article information

DOI
https://doi.org/10.1039/C3CC41619D
Article type
Communication
Submitted
04 Mar 2013
Accepted
11 Mar 2013
First published
13 Mar 2013

Chem. Commun., 2013,49, 3643-3645

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A sensitive SERS assay of L-histidine via a DNAzyme-activated target recycling cascade amplification strategy

S. Ye, Y. Guo, J. Xiao and S. Zhang, Chem. Commun., 2013, 49, 3643 DOI: 10.1039/C3CC41619D

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