Issue 6, 2013
From the journal:

RSC Advances

Solvent free, Ni-nanoparticle catalyzed greener synthesis and photophysical studies of novel 2H-indazolo[2,1-b] phthalazine-trione derivatives†

Mithu Saha,a   Smritakshi Phukan,a   Ramen Jamatia,a   Sivprasad Mitraa  and  Amarta Kumar Pal*a  

* Corresponding authors

a Department of Chemistry, North-Eastern Hill University, Mawlai Campus, Shillong 793022, India
E-mail: amartya_pal22@yahoo.com, akpal@nehu.ac.in
Fax: +91 364 2550076
Tel: +91 364 2307930 ext 2606

Abstract

A nickel nanoparticle (NPs) catalyzed one-pot three component reaction of phthalhydrazide, dimedone and aryl aldehydes under solvent free conditions has been reported. The present approach offers the advantages of simple methodology, clean and mild reaction conditions, short reaction time, low environmental impact, high yield, and excellent purity. The synthesized compounds (2H-indazolo[2,1-b] phthalazine-trione) are found to be suitable candidates for efficient fluorogenic assays to monitor bio-chemical environments.

Graphical abstract: Solvent free, Ni-nanoparticle catalyzed greener synthesis and photophysical studies of novel 2H-indazolo[2,1-b] phthalazine-trione derivatives

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Article information

DOI
https://doi.org/10.1039/C2RA22396A
Article type
Communication
Submitted
04 Oct 2012
Accepted
23 Nov 2012
First published
23 Nov 2012

RSC Adv., 2013,3, 1714-1721

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Solvent free, Ni-nanoparticle catalyzed greener synthesis and photophysical studies of novel 2H-indazolo[2,1-b] phthalazine-trione derivatives

M. Saha, S. Phukan, R. Jamatia, S. Mitra and A. K. Pal, RSC Adv., 2013, 3, 1714 DOI: 10.1039/C2RA22396A

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