Issue 10, 2012

Electroplated porous polypyrrole nanostructures patterned by colloidal lithography for drug-delivery applications

Abstract

Porous nanostructures of polypyrrole (Ppy) were fabricated using colloidal lithography and electrochemical techniques for potential applications in drug delivery. A sequential fabrication method was developed and optimized to maximize the coverage of the Ppy nanostructures and to obtain a homogeneous layer over the substrate. This was realized by masking with electrophoretically-assembled polystyrene (PS) nanospheres and then electroplating. Drug/biomolecule adsorption and the release characteristics for the porous nanostructures of Ppy were investigated using rhodamine B (Rh-B). Rh-B is an easily detectable small hydrophobic molecule that is used as a model for many drugs or biological substances. The porous Ppy nanostructures with an enhanced surface area exhibited higher Rh-B loading capacity than bulk planar films of Ppy. Moreover, tunability of surface morphology for further applications (e.g., sensing, cell adhesion) was demonstrated.

Graphical abstract: Electroplated porous polypyrrole nanostructures patterned by colloidal lithography for drug-delivery applications

Supplementary files

Article information

Article type
Paper
Submitted
24 Jan 2012
Accepted
14 Feb 2012
First published
24 Feb 2012

Nanoscale, 2012,4, 3083-3088

Electroplated porous polypyrrole nanostructures patterned by colloidal lithography for drug-delivery applications

J. Pokki, O. Ergeneman, K. M. Sivaraman, B. Özkale, M. A. Zeeshan, T. Lühmann, B. J. Nelson and S. Pané, Nanoscale, 2012, 4, 3083 DOI: 10.1039/C2NR30192J

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