Issue 40, 2012

Polymer–gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(iii) complexes

Abstract

We present a new synthetic strategy to produce Gd(III)-decorated gold nanoparticles (AuNPs) for potential use as bimodal contrast agents (CA) for computed X-ray tomography (CT) and magnetic resonance imaging (MRI). The hybrid AuNPs exhibit high molar relaxivities (>12 000 mM−1 s−1 per particle), indicative of highly efficient CT/MRI CAs.

Graphical abstract: Polymer–gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(iii) complexes

Supplementary files

Article information

Article type
Communication
Submitted
27 Jul 2012
Accepted
30 Aug 2012
First published
14 Sep 2012

J. Mater. Chem., 2012,22, 21382-21386

Polymer–gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(III) complexes

M. Beija, Y. Li, H. T. Duong, S. Laurent, L. V. Elst, R. N. Muller, A. B. Lowe, T. P. Davis and C. Boyer, J. Mater. Chem., 2012, 22, 21382 DOI: 10.1039/C2JM34999J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements